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Myozenin 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11450-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888533

  • 1281.92 NOK / 20µL
Estimated Shipment: 15-12-2022
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Description

Description

Proteintech′s Myozenin-2 antibody 11450-1-AP was raised against full-length protein of human origin and is able to detect a band of approximately 34 kDa in Western blotting.

The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to alpha-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
Specifications

Specifications

Myozenin 2
Polyclonal
Unconjugated
MYOZ2
C4orf5, Calsarcin-1, FATZ related protein 2, MYOZ2, Myozenin 2
Rabbit
Antigen Affinity Chromatography
RUO
295426, 51778, 59006
-20°C
Liquid
Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9JJW5, Q9NPC6
Myoz2
Myozenin 2 Fusion Protein Ag2008
20 μL
Primary
Mouse, Human, Rat
Antibody
IgG
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