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Description
Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.
Specifications
Specifications
| Antigen | MYH6 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.43 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | MYH6 |
| Gene Accession No. | P02563, P13533, Q02566 |
| Gene Alias | alpha MHC, ASD3, MYH6, MYHC, MyHC alpha, MYHCA, Myosin 6, Myosin heavy chain 6 |
| Gene Symbols | Myh6 |
| Show More |
Product Title
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