missing translation for 'onlineSavingsMsg'
Learn More

MUTYH Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19650-1-AP-150UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16889124

  • 3468.15 NOK / 150µL
Estimated Shipment: 13-12-2022
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

MYH (mutY homolog (E. coli )) is a DNA glycosylase mismatch repair enzyme that in conjunction with mutM (OGG1), cleaves adenine residues paired with either oxidized (8-hydroxyguanines) or non-modified guanines in order to correct A/G and A/C mismatches. Repair of most modified and mispaired bases in the genome is initiated by DNA glycosylases, which bind and cleave N-glycosyl bonds to initiate base excision repair. MYH is crucial for the avoidance of mutations resulting from oxidative DNA damage. Multiple N-terminal splice variants of MYH exist in mammalian cells. Increasing levels of MYH in A549 cells exposed to oxygen and infrared radiation leads to improvements in cell survival. Biallelic MYH germ-line mutations predispose humans to colorectal adenomas and carcinomas. MYH is abundant in neurons where mitochondrial genomes exposed to reactive oxygen species (ROS) that damage DNA must maintain integrity over the entire mammalian life span.
Specifications

Specifications

MUTYH
Polyclonal
Unconjugated
MUTYH
hMYH, MutY homolog, mutY homolog (E. coli), MUTYH, MYH
Rabbit
Antigen Affinity Chromatography
RUO
170841, 4595, 70603
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.28 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8R5G2, Q99P21, Q9UIF7
MUTYH
MUTYH Fusion Protein Ag7526
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
Videos
SDS
Documents
Certificates
Special Offers

Special Offers