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MRP5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19503-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16889024

  • 3468.15 NOK / 150µL
Estimated Shipment: 20-12-2022
to see stock.

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Description

Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.
Specifications

Specifications

MRP5
Polyclonal
Unconjugated
ABCC5
ABC33, ABCC5, MOAT C, MOATC, MRP5, pABC11, SMRP
Rabbit
Antigen Affinity Chromatography
RUO
10057, 116721, 27416
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.46 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O15440, Q9QYM0, Q9R1X5
Abcc5
Peptide
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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SDS
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Documents

Certificates
Special Offers

Special Offers