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Mozavaptan, MedChemExpress

Product Code. 16473527
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Product Code. 16473527 Supplier Medchem Express Supplier No. HY18346

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Description

MedChemExpress Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V2 receptor antagonist with an IC50 of 14 nM.

Mozavaptan shows ∼85-fold selectivity for V2 receptor over V1 receptor (IC50 of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment.

Specifications

Chemical Name or Material Mozavaptan
Physical Form Solid
CAS 137975-06-5
Color Light Yellow
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C27H29N3O2
For Use With (Application) Cancer-programmed cell death
Synonym OPC-31260
Solubility Information DMSO : 6.2 mg/mL (14.50 mM; Need warming)
SMILES CC1=CC=CC=C1C(NC2=CC=C(C(N3C(C=CC=C4)=C4C(N(C)C)CCC3)=O)C=C2)=O
Molecular Weight (g/mol) 427.54
Formula Weight 427.54
Percent Purity 98.12%
Grade Research
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