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Invitrogen™ Mouse TPO (Thrombopoietin), AOF Recombinant Protein
E. coli Recombinant Protein
Brand: Invitrogen™ RP87755
Additional Details : Weight : 0.01000kg
Description
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.- Purity: >95% by SDS-Page
- Endotoxin Concentration: AX41 ≤EUs/μg
- Protein Length: 175 aa.
- Biological Activity: <5 ng/mL
- Molecular Weight: 18.7 kDa
- Animal Origin Free: Yes
Specifications
| P40226 | |
| Lyophilized | |
| 21832 | |
| Mouse Thrombopoietin (TPO), AOF | |
| 1 mg | |
| -20°C | |
| C-mpl ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; megakaryocyte stimulating factor; MGDF; MKCSF; ML; MPL ligand; Mpllg; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; THCYT1; THPO; Thrombopoietin; TPO | |
| Mouse | |
| Yes |
| Control, ELISA, Functional Assay assay, Gel Shift, Western Blot | |
| 10 mM sodium phosphate with no preservative | |
| 18.7 kDa | |
| >95% | |
| E. coli | |
| RUO | |
| THPO | |
| Unlabeled |