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STEMCELL Technologies Mouse Recombinant IL-6
Interleukin 6
Brand: STEMCELL Technologies 78052
Additional Details : Weight : 0.00110kg
Description
- Interleukin 6 (IL-6) is a pleiotropic growth factor with a wide range of biological activities in immune regulation, hematopoiesis, and oncogenesis
- IL-6 is produced by a variety of cell types including T cells, B cells, monocytes and macrophages, fibroblasts, hepatocytes, vascular endothelial cells, and various tumor cell lines
- On its own or in combination with other factors such as IL-2 and interferon-γ, IL-6 stimulates the proliferation of B cells, T cells, and hybridoma cells
- In combination with cytokines such as IL-3, GM-CSF, and SCF, IL-6 has been shown to promote hematopoietic progenitor cell proliferation and differentiation in vitro
- IL-6 signals through a cell surface type I cytokine receptor complex consisting of the ligand-binding IL-6α (CD126) and the signal-transducing gp130 subunits
- The binding of IL-6 to its receptor system includes activation of the JAK/STAT signaling pathway
Specifications
| B cell differentiation factor, BSF-2, IFN-β2, Interleukin-6 | |
| 100 μg | |
| Airway Cells; B Cells; Hematopoietic Stem and Progenitor Cells; Intestinal Cells; Lymphocytes; Neurons; Pluripotent Stem Cells; T Cells | |
| ≥95% |