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STEMCELL Technologies Mouse Recombinant IL-10

Interleukin 10

Brand:  STEMCELL Technologies 78079.1

Additional Details : Weight : 0.00110kg

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Product Code. 17109521

  • 8288.64 NOK / 50µg
Estimated Shipment: 20-10-2023
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  • Interleukin 10 (IL-10) is the founding member of the IL-10 family of class II cytokines
  • All of the IL-10 cytokine family members have a four-helix bundle consisting of α-helical folds
  • Upon binding to its receptor, IL-10 activates signaling through JAK1 and STAT3
  • It is produced by dendritic cells, macrophages, and CD4+ T regulatory cells, as well as mast cells, NK cells, neutrophils, and regulatory B cells, under specific stimulating conditions
  • IL-10 can inhibit the activation of certain immune cells while it promotes the function of B cells, and facilitates the healing process
  • Specifically, this cytokine is important for the function of T regulatory cells as it is a potent suppressor of effector T cell proliferation and cytokine production
  • Also, IL-10 produced by a subset of macrophages inhibits activation and production of pro-inflammatory cytokines by neighboring macrophages, thus allowing a level of self-regulation


B-TCGF, CSIF, Cytokine synthesis inhibitory factor, Interleukin-10, TGIF
50 μg
Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Myeloid Cells; Neurons; T Cells; T Cells, CD4+; T Cells, Regulatory


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