missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ SARS-CoV-2 Spike Protein (S-RBD) (aa330-524), His Tag, Recombinant Protein

E. coli Recombinant Protein

Brand:  Invitrogen™ A42555

Additional Details : Weight : 0.00200kg

 View more versions of this product

Product Code. 16449485

  • 538.00 NOK / 5µg
Estimated Shipment: 06-01-2023
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

EGF (Epidermal growth factor) exerts its actions by binding to the EGF Receptor, a 170 kDa protein kinase. Activation of EGFR initiates diverse cellular pathways in response to toxic environmental stimuli, or to EGF binding to the receptor, the EGFR forms homo- or heterodimers with other family members. Each dimeric receptor complex initiates a distinct signaling pathway by recruiting different Src homology 2 (SH2) containing effector proteins. EGF is far and wide expressed in kidney, cerebrum, prostrate and salivary glands. EGF acts as a potent mitogenic factor and the phosphorylated receptor recruits adapter proteins like GRB2 that activates complex downstream signaling cascades. EGF activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STAT modules. Research studies suggest the protein may also play important role in activating the NF-kappa-B signaling cascade. Defects in the EGGF gene are the cause of hypomagnesemia type 4 and dysregulation has been associated with the growth and progression of certain cancers.
Specifications

Specifications

P01133
Lyophilized
1950
>90%
E. coli
RUO
EGF
Unlabeled
Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot
protein with 0.02% Tween 80, 140 mM NaCl, 2.7 mM KCl, 5% mannitol, 5% trehalose and no preservative; pH 7.4
Mouse EGF
5 µg
-20°C
AI790464; beta-urogastrone; Egf; Epidermal growth factor; epidermal growth factor (beta-urogastrone); H-EGF; HOMG4; Pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF); URG; Urogastrone
Human
Yes
Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers