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ACROBiosystems Mouse CTGF / CCN2 Protein, His Tag

Brand:  ACROBiosystems CTF-M52Hc-100ug

Additional Details : Weight : 0.00010kg

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Product Code. 16447459

  • 4432.75 NOK / 100µg
Estimated Shipment: 18-01-2023
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Description

Description

Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.3 kDa. The protein migrates as 37-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_034347.2
37.3 kDa
100 µg
Gln 26 - Ala 348
CCN2,NOV2,HCS24,IGFBP8,IBP-8,IGFBP-8,IGF-binding protein 8
Unconjugated
Tris with Potassium glutamate and Arginine, pH7.0
HEK293
Mouse
Powder
>90% as determined by SDS-PAGE
Mouse CTGF, His Tag (CTF-M52Hc) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Ala 348 (Accession # P29268-1).
-20°C
CTGF
His Tag
Less than 1.0 EU / µg by the LAL method.
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