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LCK, Mouse, Clone: LCK-01, Abnova™

Product Code. 16069905
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Quantity:
100 μg
Unit Size:
100µg
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16069905 100 μg 100µg
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Product Code. 16069905 Supplier Abnova Supplier No. MAB0912.100ug

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Description

Mouse monoclonal antibody raised against synthetic peptide of LCK.

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq

Specifications

Antigen LCK
Applications Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone LCK-01
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against synthetic peptide of LCK.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (0.09% sodium azide)
Gene LCK
Gene Alias YT16/p56lck/pp58lck
Gene Symbols LCK
Host Species Mouse
Immunogen A synthetic peptide (conjugated with KLH) corresponding to amino acids 22-36 of human LCK.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3932
Test Specificity This antibody LCK-01 recognizes defined epitope of Lck, a 56 KDa Src-family protein tyrosine kinase.
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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