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Momelotinib sulfate, MedChemExpress

Product Code. 16464318
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Product Code. 16464318 Supplier Medchem Express Supplier No. HY10962

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Description

MedChemExpress Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM).

Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM).

Specifications

Chemical Name or Material Momelotinib sulfate
CAS 1056636-06-6
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C23H26N6O10S2
Quantity 10 mg
Synonym CYT387 sulfate salt
Solubility Information DMSO : 220 mg/mL (360.29 mM; Need ultrasonic) ∣H2O : 100 mg/mL (163.77 mM; Need ultrasonic)
SMILES O=C(NCC#N)C(C=C1)=CC=C1C2=NC(NC(C=C3)=CC=C3N4CCOCC4)=NC=C2.O=S(O)(O)=O.O=S(O)(O)=O
Molecular Weight (g/mol) 610.62
Formula Weight 610.62
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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