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Invitrogen™ MMP7 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA586185
This item is not returnable.
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Description
Purity is > 95% by SDS-PAGE.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
Specifications
| MMP7 | |
| Polyclonal | |
| Unconjugated | |
| MMP7 | |
| HGNC:7174; MAT; Matrilysin; matrilysin, uterine; matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP; MMP 7; MMP7; Mmp-7; MMP-7 protein; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 17393, 25335, 4316 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Western Blot | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide; pH 7.2 | |
| P09237, P50280, Q10738 | |
| MMP7 | |
| Synthetic peptide, corresponding to amino acids 211-260 of Human MMP-7. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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