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ML141, MedChemExpress

Product Code. 16485318
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Product Code. 16485318

Brand: Medchem Express HY12755

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MedChemExpress ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines.

ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines.

Specifications

Chemical Name or Material ML141
CAS 71203-35-5
Color Off-White
Purity Grade Notes Research
Molecular Formula C22H21N3O3S
Quantity 10 mg
Synonym CID-2950007
Solubility Information DMSO : ≥ 55 mg/mL (134.97 mM)
SMILES O=S(C1=CC=C(N2N=C(C3=CC=CC=C3)CC2C4=CC=C(OC)C=C4)C=C1)(N)=O
Molecular Weight (g/mol) 407.49
Formula Weight 407.49
Percent Purity 98.03%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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