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Thermo Scientific Chemicals Mitoxantrone Dihydrochloride

Product Code. 15437659
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Quantity:
50 mg
Unit Size:
50mg
Product Code. Quantity unitSize
15437659 50 mg 50mg
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Product Code. 15437659

Brand: Thermo Scientific Chemicals J66341.MF

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Description

CAS: 70476-82-3 | C22H30Cl2N4O6, C22H28N4O6.2HCl | 517.40 g/mol

Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic cytostatic anthraquinone derivative. Induces DNA damage by intercalating into DNA and inhibiting Topo II (topoisomerase II). Mitoxantrone dihydrochloride induces interstrand DNA cross-links and DNA-protein cross-links in cellular systems. Mitoxantrone dihydrochloride has recently been shown to be an inhibitor of DNA methylation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

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Specifications

Quantity 50 mg
Description Blue to black
Content And Storage -30°C to -10°C
CAS 70476-82-3
Molecular Formula C22H28N4O6.2HCl, C22H30Cl2N4O6
Formula Weight 517.40
Synonym 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride;
Solubility Soluble to 5 mM in water and to 75 mM in DMSO
Product Type Mitoxantrone dihydrochloride
Form Crystalline solid
InChI Key ZAHQPTJLOCWVPG-UHFFFAOYSA-N
SMILES [H+].[H+].[Cl-].[Cl-].OCCNCCNC1=CC=C(NCCNCCO)C2=C1C(=O)C1=C(O)C=CC(O)=C1C2=O
IUPAC Name dihydrogen 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-dihydroanthracene-9,10-dione dichloride
Molecular Weight (g/mol) 517.40
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