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Description
Expression of the midnolin gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The midnolin encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the midnolin was studied by using midnolin-green fluorescent protein (GFP) fusion proteins. Midnolin was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the midnolin. May be involved in regulation of genes related to neurogenesis in the nucleolus.
Specifications
Specifications
| Antigen | MIDN |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.33 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | MIDN |
| Gene Accession No. | D4AE48, Q3TPJ7, Q504T8 |
| Gene Alias | Midbrain nucleolar protein, MIDN, midnolin |
| Gene Symbols | Midn |
| Show More |
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