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Methotrexate, MedChemExpress

Product Code. p-200100578
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Product Code. 16486476 Supplier Medchem Express Supplier No. HY14519

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Description

MedChemExpress Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).

Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).

Specifications

Chemical Name or Material Methotrexate
CAS 59-05-2
Color Light Brown
Purity Grade Notes Research
Molecular Formula C20H22N8O5
Quantity 100 mg
Synonym Amethopterin CL14377 WR19039
Solubility Information DMSO : ≥ 50 mg/mL (110.03 mM)
SMILES NC1=NC(N)=C2C(N=CC(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=N1
Molecular Weight (g/mol) 454.44
Formula Weight 454.44
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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