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Melphalan, Tocris Bioscience™
Description
DNA alkylating agent; induces cytotoxicity through the formation of stable interstrand and intrastrand crosslinks within DNA. Inhibits growth of PC-3 cells (IC50 values are 0.074 and 0.77 μg/ml for sequential dosing and single dosing respectively).
Specifications
Specifications
| CAS | 148-82-3 |
| Molecular Formula | C13H18Cl2N2O2 |
| Quantity | 50 mg |
| Synonym | melphalan, alkeran, melfalan, phenylalanine mustard, l-sarcolysine, l-pam, l-sarcolysin, l-phenylalanine mustard, levofalan, p-l-sarcolysin |
| InChI Key | SGDBTWWWUNNDEQ-LBPRGKRZSA-N |
| SMILES | C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl |
| IUPAC Name | (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid |
| Molecular Weight (g/mol) | 305.199 |
| PubChem CID | 460612 |
| ChEBI | CHEBI:28876 |
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