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MCM7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11225-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888153

  • 3468.15 NOK / 150µL
Estimated Shipment: 14-12-2022
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Description

Description

MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Specifications

Specifications

MCM7
Polyclonal
Unconjugated
MCM7
CDABP0042, CDC47, CDC47 homolog, MCM2, MCM7, P1.1 MCM3, P1CDC47, P85MCM, PNAS 146
Rabbit
Antigen Affinity Chromatography
RUO
17220, 288532, 4176
-20°C
Liquid
Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Flow Cytometry
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P33993, Q61881
Mcm7
MCM7 Fusion Protein Ag1730
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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