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MCM4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13043-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16891054

  • 3468.15 NOK / 150µL
Estimated Shipment: 16-12-2022
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Description

Description

This antibody is a rabbit polyclonal antibody raised against the C-terminal 350 aa sequence of MCM4 protein.

The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
Specifications

Specifications

MCM4
Polyclonal
Unconjugated
MCM4
CDC21, CDC21 homolog, CDC54, hCdc21, MCM4, P1 CDC21
Rabbit
Antigen Affinity Chromatography
RUO
17217, 29728, 4173
-20°C
Liquid
Western Blot, Immunoprecipitation
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P33991, P49717
Mcm4
MCM4 Fusion Protein Ag3703
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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