missing translation for 'onlineSavingsMsg'
Learn More
Learn More
MCM4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13043-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
This antibody is a rabbit polyclonal antibody raised against the C-terminal 350 aa sequence of MCM4 protein.
The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.Specifications
MCM4 | |
Polyclonal | |
Unconjugated | |
MCM4 | |
CDC21, CDC21 homolog, CDC54, hCdc21, MCM4, P1 CDC21 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
17217, 29728, 4173 | |
-20°C | |
Liquid |
Immunoprecipitation, Western Blot | |
0.17 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P33991, P49717 | |
Mcm4 | |
MCM4 Fusion Protein Ag3703 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |