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MAPK15 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13452-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.Specifications
| MAPK15 | |
| Polyclonal | |
| Unconjugated | |
| MAPK15 | |
| ERK 7, ERK 8, ERK7, ERK8, MAP kinase 15, MAPK 15, MAPK15 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 225689, 286997, 332110 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q80Y86, Q8TD08, Q9Z2A6 | |
| Mapk15 | |
| MAPK15 Fusion Protein Ag4255 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |