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MAPK15 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13452-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16891674

  • 3468.15 NOK / 150µL
Estimated Shipment: 15-12-2022
to see stock.

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Description

Description

The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.
Specifications

Specifications

MAPK15
Polyclonal
Unconjugated
MAPK15
ERK 7, ERK 8, ERK7, ERK8, MAP kinase 15, MAPK 15, MAPK15
Rabbit
Antigen Affinity Chromatography
RUO
225689, 286997, 332110
-20°C
Liquid
Western Blot, Immunoprecipitation
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q80Y86, Q8TD08, Q9Z2A6
Mapk15
MAPK15 Fusion Protein Ag4255
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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Special Offers

Special Offers