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  4. Invitrogen™ Human MAP3K11 (MLK3), GST Tag Recombinant Protein

Invitrogen™ Human MAP3K11 (MLK3), GST Tag Recombinant Protein

Product Code. 12634770
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Quantity:
10 μg
100 μg
Unit Size:
100µg
10µg
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Product Code. 12634770

Brand: Invitrogen™ PR6962A

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length.

MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q16584
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with 2mM DTT, 0.02% Triton X-100, 50% glycerol, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
Gene ID (Entrez) 4296
Molecular Weight (g/mol) 120.1 kDa
Name Human MAP3K11 (MLK3), GST Tag
pH Range 7.5
Purification Method Purified
Quantity 100 μg
Source Human
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase
Common Name MLK3
Gene Symbol MAP3K11
KinaseFamily MLK Kinase Family
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser⁄Thr Kinases: TKL Group
Shipping Condition Dry Ice
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
Protein Subtype Serine/Threonine Kinases
Research Category Immunology, Oncology, Signal Transduction
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