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LRWD1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 19546-1-AP-150UL
Additional Details : Weight : 0.00010kg
Description
The antibody recognizes the N-term of LRWD1.
Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.Specifications
| LRWD1 | |
| Polyclonal | |
| Unconjugated | |
| LRWD1 | |
| LRWD1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 222229, 71735 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 0.35 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q8BUI3, Q9UFC0 | |
| Lrwd1 | |
| Peptide | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |