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LDHB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 19988-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16889464

  • 3468.15 NOK / 150µL
Estimated Shipment: 15-12-2022
to see stock.

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Description

Description

The antibody has no cross reaction with LDHA and LDHC.

Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84-89% sequence similarities and 69-75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers.
Specifications

Specifications

LDHB
Polyclonal
Unconjugated
LDHB
lactate dehydrogenase B, LDH B, LDH H, LDH heart subunit, LDHB, TRG 5
Rabbit
Antigen Affinity Chromatography
RUO
16832, 24534, 3945
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P07195, P16125, P42123
Ldhb
Peptide
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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