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  6. LDHB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

LDHB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16899464 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16899464 20 μL 20µL
16889464 150 μL 150µL
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Product Code. 16899464

Brand: Proteintech 199881AP20UL

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This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

The antibody has no cross reaction with LDHA and LDHC.

Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84-89% sequence similarities and 69-75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers.

Specifications

Antigen LDHB
Applications Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LDHB
Gene Accession No. P07195, P16125, P42123
Gene Alias lactate dehydrogenase B, LDH B, LDH H, LDH heart subunit, LDHB, TRG 5
Gene Symbols Ldhb
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16832, 24534, 3945
Target Species Mouse, Rat, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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