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Lazabemide, MedChemExpress

Product Code. 16462137
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Product Code. 16462137 Supplier Medchem Express Supplier No. HY14201

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Description

MedChemExpress Lazabemide (Ro 19-6327) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease.

Lazabemide (Ro 19-6327) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease.

Specifications

Chemical Name or Material Lazabemide
CAS 103878-84-8
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C8H10ClN3O
Quantity 50 mg
Synonym Ro 19-6327
Solubility Information DMSO : 5 mg/mL (25.05 mM; Need ultrasonic)
SMILES ClC1=CC=C(C(NCCN)=O)N=C1
Molecular Weight (g/mol) 199.64
Formula Weight 199.64
Percent Purity 99.76%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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