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Thermo Scientific™ LanthaScreen™ TR-FRET Glucocorticoid Receptor Competitive Binding Kit
Description
The LanthaScreen™ TR-FRET Glucocorticoid Receptor Competitive Binding Assay Kit provides a sensitive and robust method for high-throughput screening (HTS) of ligands for glucocorticoid receptor (GR). The kit uses a human GR ligand-binding domain (GR-LBD) tagged with glutathione S-transferase (GST) (also available separately), a terbium-labeled anti-GST antibody, and a fluorescent small-molecule GR ligand (Fluormone™ GS1) in a homogeneous mix-and-read assay format.
The Lanthascreen Gluococorticoid Receptor Competitive Binding Assay is:
- Complete & ready-to-use out of the box—all reagents included, just add your test compounds
- High throughput compatible—TR-FRET assays in a 384-well plate
- Convenient—components available in bulk sizes for larger screening needs
Specifications
Specifications
| For Use With (Application) | Competitive Binding Assay, Nuclear Receptor Assay |
| Quantity | 800 x 20 μL assays |
| Content And Storage | • GR Ligand Binding Domain Recombinant Protein, 1 tube (store at -68°C to -85°C) • Fluormone GS1, 1 tube (-5°C to -30°C) • Buffer, 2 bottles (-5°C to -30°C) • Tb-Anti-GST Ab, 1 tube (-5°C to -30°C) • GR Stabilizing Peptide, 5 tubes (-5°C to -30°C) • DTT, 1 tube (-5°C to -30°C) |
| Product Line | LanthaScreen |
| Ligand | GR |
| Product Type | TR-FRET Glucocorticoid Receptor Competitive Binding Kit |
| No. of Assays | 800 x 20 μL |
For Research Use Only. Not for use in diagnostic procedures.
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