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Description
The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.
Host Species: Mouse
Clone: UJ127
Isotype: IgG1/k
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Homogenous suspension of 16-week human fetal brain
Molecular Weight: 220-240kDa
Positive Control: IMR-5 cells Neuroblastoma
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native and denatured)
Note:
USA: RUO; Int'l: RUO
Specifications
Specifications
| Antigen | L1 Cell Adhesion Molecule Ab-1 |
| Applications | Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | UJ127 |
| Concentration | 200μg/mL |
| Conjugate | Unconjugated |
| Host Species | Mouse |
| Immunogen | Homogenous suspension of 16 week human fetal brain |
| Quantity | 500 μL |
| Regulatory Status | RUO |
| Show More |
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