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  4. Invitrogen™ Human KSR2, GST Tag Recombinant Protein

Invitrogen™ Human KSR2, GST Tag Recombinant Protein

Product Code. p-7181392
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
100µg
10µg
1mg
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Product Code. 15950283

Brand: Invitrogen™ A30500

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This KSR2 recombinant human protein (554-end) was expressed in insect cells. KSR2 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Catalytic The gene accession number for KSR2 is NP_775869.3.

KSR2 serine/threonine kinase or kinase suppressor of Ras 2 specifically regulates the activity of MEKK3 and COT but not other members of the MAP3K family. KSR interacts with a regulatory Raf molecule in cis to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf molecule in trans. Blocks MAP3K8 kinase activity and MAP3K8- mediated signaling. Acts as a negative regulator of MAP3K3- mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
TRUSTED_SUSTAINABILITY

Tekniske data

Accession Number Q6VAB6
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 10mM glutathione, 150mM NaCl, 0.1mM EDTA, 0.1mM PMSF, 0.25mM DTT, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 283455
Molecular Weight (g/mol) 72.1 kDa
Name Human KSR2, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 10 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias hKSR2; Kinase suppressor of Ras 2; ksr2; RGD1562674; testes-kinase suppressor of ras 2 isoform
Common Name KSR2
Gene Symbol KSR2
KinaseFamily MAP Kinases
Protein Length 544-end
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence 544-end
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Shipping Condition Dry Ice
Expression System Insect cells
Protein Form Recombinant, Active, Catalytic
Form Liquid
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