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KRAS-2A Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 16156-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16885684

  • 3468.15 NOK / 150µL
Estimated Shipment: 16-12-2022
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Description

Description

This antibody is specific for KRAS-2A, which also named as KRAS-4A.

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
Specifications

Specifications

KRAS-2A
Polyclonal
Unconjugated
KRAS
C K RAS, c Ki ras, GTPase KRas, K Ras 2, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS, KRAS1, KRAS2, KRAS2A, KRAS2B speicifc, KRAS4A, Krasa, Krasb, NS3, RASK2
Rabbit
Antigen Affinity Chromatography
RUO
3845
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Flow Cytometry
0.69 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P01116
KRAS
Peptide
150 μL
Primary
Human
Antibody
IgG
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