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![Invitrogen™ Human KIT [V560G], GST Tag Recombinant Protein Quantity: 100 μg](https://assets.fishersci.com/TFS-Assets/LSG/product-images/Cell_Bio_Rec_Prot_Invitrogen_Vial.jpg-650.jpg)
Invitrogen™ Human KIT [V560G], GST Tag Recombinant Protein
This KIT V560G Recombinant Human Protein (544-end) was expressed in insect cells.
Brand: Invitrogen™ A32869
Additional Details : Weight : 0.00900kg
Description
KIT V560G KIT receptor tyrosine kinase is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth.- Validated for use with the Z’-LYTE™ assay
- Available in multiple pack sizes for convenient use
Specifications
| NP_000213 | |
| Kit | |
| 100 μg | |
| aa 544 - end | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Insect | |
| Liquid |
| Kinase Assay | |
| 75.1 kDa | |
| PDGFR Kinase Family | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Recombinant, Active, Catalytic, Mutant |