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Tocris Bioscience™ KG 5

PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
Brand: Tocris Bioscience™ 5260/10
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Description
KG 5 is a PDGFRβ and B-Raf allosteric inhibitor. Also inhibits c-Raf, FLT3 and KIT. Disrupts blood vessel formation in zebrafish embryos and inhibits angiogenesis in a mouse angiogenesis model. Inhibits growth of renal and pancreatic tumors in mice. Also arrests cells in prometaphase. Orally available.Specifications
| 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine | |
| 877874-85-6 | |
| 10 mg |
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