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KDM5C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14426-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16893054

  • 3468.15 NOK / 150µL
Estimated Shipment: 20-12-2022
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Description

Description

Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.; Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
Specifications

Specifications

KDM5C
Polyclonal
Unconjugated
KDM5C
DXS1272E, Histone demethylase JARID1C, JARID1C, KDM5C, lysine (K) demethylase 5C, Lysine specific demethylase 5C, MRXJ, MRXSJ, Protein SmcX, Protein Xe169, SMCX, XE169
Rabbit
Antigen Affinity Chromatography
RUO
20591, 317432, 8242
-20°C
Liquid
Western Blot, Immunofluorescence, Immunocytochemistry
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P41229, P41230
Kdm5c
KDM5C Fusion Protein Ag5791
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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