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JNJ-10229570, MedChemExpress

Product Code. 16480457
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Product Code. Quantity unitSize
16480457 50 mg 50mg
16492946 25 mg 25mg
16446807 5 mg 5mg
16425076 100 mg 100mg
16404108 10 mg 10mg
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Product Code. 16480457

Brand: Medchem Express HY107139

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Description

MedChemExpress JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.

JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.

Specifications

Chemical Name or Material JNJ-10229570
CAS 524923-88-4
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C22H19N3O2S
Quantity 50 mg
Solubility Information DMSO : 62.5 mg/mL (160.47 mM; Need ultrasonic)
SMILES COC1=C(C=CC=C1)C(N(C2=C(C=CC=C2)OC)S/3)=NC3=N\C4=CC=CC=C4
Molecular Weight (g/mol) 389.47
Formula Weight 389.47
Percent Purity 98.0%
Grade Research
Physical Form Solid
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