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Description
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
Specifications
Specifications
| Antigen | JAM2 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.39 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | JAM2 |
| Gene Accession No. | P57087, Q9JI59 |
| Gene Alias | C21orf43, CD322, JAM 2, JAM B, JAM2, JAMB, junctional adhesion molecule 2, Junctional adhesion molecule B, PRO245, VE JAM, VEJAM |
| Gene Symbols | Jam2 |
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Product Title
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