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ITCH Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 20920-1-AP-20UL
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Description
Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT domain. It can act as a transcriptional corepressor of p45/NFE2 and may participate in the regulation of immune responses by modifying Notch-mediated signaling. It is highly similar to the mouse Itch protein, which has been implicated in the regulation and differentiation of erythroid and lymphoid cells.Specifications
| ITCH | |
| Polyclonal | |
| Unconjugated | |
| ITCH | |
| AIF4, AIP4, ITCH, NAPP1, NFE2 associated polypeptide 1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 16396, 83737 | |
| -20°C | |
| Liquid |
| Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation | |
| 0.23 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q8C863, Q96J02 | |
| ITCH | |
| ITCH Fusion Protein Ag15120 | |
| 20 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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