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IRGC Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14090-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16892574

  • 1281.92 NOK / 20µL
Estimated Shipment: 16-12-2022
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Description

Description

Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans.
Specifications

Specifications

IRGC
Polyclonal
Unconjugated
IRGC
CINEMA, Iigp5, Interferon inducible GTPase 5, IRGC, IRGC1, R30953_1
Rabbit
Antigen Affinity Chromatography
RUO
210145, 308428, 56269
-20°C
Liquid
Western Blot
0.16 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q6AYF9, Q6NXR0, Q8C262
IRGC
IRGC Fusion Protein Ag5279
20 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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