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IL12RB1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13287-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16891414

  • 3468.15 NOK / 150µL
Estimated Shipment: 19-12-2022
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Description

Description

The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Specifications

Specifications

IL12RB1
Polyclonal
Unconjugated
IL12RB1
CD212, IL 12 receptor beta component, IL 12 receptor subunit beta 1, IL 12R beta 1, IL 12R BETA1, IL 12R subunit beta 1, IL 12RB1, IL-12 R beta 1, IL12R, IL12RB, IL12RB1
Rabbit
Antigen Affinity Chromatography
RUO
3594
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P42701
IL12RB1
IL12RB1 Fusion Protein Ag3983
150 μL
Primary
Human
Antibody
IgG
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