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Invitrogen™ IL-10 Monoclonal Antibody (945A5A10), Biotin
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Product Code. 10018582
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Quantity:
100 μg
Unit Size:
Each
Product Code. Quantity unitSize
10018582 100 μg Each
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This item is not returnable. View return policy

Product Code. 10018582

Brand: Invitrogen™ AHC7109

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This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

This product is recommended as a detection antibody in Sandwich ELISA applications.

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
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Specifications

Antigen IL-10
Applications ELISA
Classification Monoclonal
Clone 945A5A10
Concentration 0.5 mg/mL
Conjugate Biotin
Formulation PBS with 5mg/mL BSA and 0.5mg/mL sodium azide; pH 7.4
Gene IL10
Gene Accession No. P22301
Gene Alias CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Gene Symbols IL10
Host Species Mouse
Immunogen Recombinant human IL-10.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3586
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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