missing translation for 'onlineSavingsMsg'
Learn More

IkB beta Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12660-1-AP-20UL

Additional Details : Weight : 0.00010kg

 View more versions of this product

Product Code. 16890494

  • 1281.92 NOK / 20µL
Estimated Shipment: 20-12-2022
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

The NF-kB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IkB proteins. Most agents that activate NF-kB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IkB. The key regulatory step in this pathway involves activation of a high molecular weight IkB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits. IKK alpha and IKK beta serve as the catalytic subunits of the kinase and IKK gamma serves as the regulatory subunit. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKK beta (Ser176 and Ser180 in IKK alpha), which causes conformational changes, resulting in kinase activation.
Specifications

Specifications

IkB beta
Polyclonal
Unconjugated
NFKBIB
I kappa B beta, IkappaBbeta, IkB B, IkB beta, IKBB, NF kappa B inhibitor beta, NF kappa BIB, NFKBIB, TR interacting protein 9, TRIP 9, TRIP9
Rabbit
Antigen Affinity Chromatography
RUO
18036, 4793, 81525
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q15653, Q60778, Q9JIA3
Nfkbib
IkB beta Fusion Protein Ag3340
20 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers