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Description
IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
Specifications
Specifications
| Antigen | IFITM1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry, Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 0.22 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | IFITM1 |
| Gene Accession No. | P13164 |
| Gene Alias | 9 27, CD225, IFI17, IFITM1, Interferon induced protein 17, Leu 13 antigen, LEU13 |
| Gene Symbols | IFITM1 |
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Product Title
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