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IDH3A Mouse anti-Canine, Human, Clone: OTI2F11, liquid, TrueMAB™
Description
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predomitly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Specifications
Specifications
| Antigen | IDH3A |
| Applications | Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | OTI2F11 |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| Gene | IDH3A |
| Gene Accession No. | P50213, P54836 |
| Gene Alias | isocitrate dehydrogenase 3 (NAD(+)) alpha |
| Gene Symbols | IDH3A |
| Show More |
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