Invitrogen™ Silencer™ Select GAPDH Positive Control siRNA

• Premium-quality siRNA, highly purified and ready to use
• Functionally tested in several common cell lines
• Include Silencer™ Select modifications for enhanced specificity
• For use in human, mouse, and rat cells

What are Silencer™ Select siRNAs?

Silencer™ Select siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemical modifications, to yield siRNAs with unrivalled efficacy, potency, and specificity. The result is fewer failed experiments due to poor silencing, and cleaner, more consistent phenotypic data.

Silencer™ Select GAPDH Positive Control siRNA:

The Silencer™ SelectGAPDH positive control is extensively validated and an ideal 'test' siRNA for those just beginning siRNA experiments, because it is validated to work in multiple cell lines. Because it targets GAPDH mRNA (a common internal control), many assays are available to measure its effects, including real-time RT-PCR as well as the Ambion™ KDalert™ GAPDH Assay Kit.

Quality Control:

Silencer™ Select siRNAs are manufactured in a state-of-the-art facility under the highest quality standards. Rigorous quality control procedures include MALDI-TOF mass spectrometry analysis and analytical HPLC to monitor purity. Each siRNA is also assessed by gel electrophoresis to confirm that the strands anneal properly.

Lipofectamine™ RNAiMAX™ Transfection Reagent (SKU 13778075)

Lipofectamine™ RNAiMAX™ Transfection Reagent is a leading transfection reagent designed specifically for RNA interference applications. The protocol can be adapted to a wide range of cells and experimental designs, including high-throughput applications. Silencer Select siRNA controls have specific chemical modifications that are designed to be used with Silencer Select siRNAs. If you are using other siRNA products, such as Silencer siRNA or Stealth RNAi siRNAs, we recommend that you use control siRNAs designed for use with those siRNAs for more reliable experimental results.