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Thermo Scientific™ Hypersil™ PREP HS C8 HPLC Columns

Product Code. 16468513 Shop All Thermo Scientific Products
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Length (Metric):
8 mm
20 mm
30 mm
50 mm
100 mm
150 mm
250 mm
Diameter (Metric):
2 mm
4.6 mm
10 mm
20 mm
25 mm
30 mm
50 mm
Particle Size:
3 μm
5 μm
10 μm
Column Format:
Guard 1/16 in.
Guard 1/8 in.
Guard Column
Preparative Column, Standard
Preparative Column, Xtended Life
Unit Size:
Each
Product Code. Length (Metric) Diameter (Metric) Particle Size Column Format unitSize
16468513 50 mm 20 mm 10 μm Preparative Column, Standard Each
16428473 50 mm 2 mm 3 μm Preparative Column, Standard Each
16438473 50 mm 4.6 mm 3 μm Preparative Column, Standard Each
16448473 100 mm 2 mm 3 μm Preparative Column, Standard Each
16458473 100 mm 4.6 mm 3 μm Preparative Column, Standard Each
16468473 150 mm 2 mm 3 μm Preparative Column, Standard Each
16478473 150 mm 4.6 mm 3 μm Preparative Column, Standard Each
16488473 250 mm 2 mm 3 μm Preparative Column, Standard Each
16498473 250 mm 4.6 mm 3 μm Preparative Column, Standard Each
16408483 50 mm 2 mm 5 μm Preparative Column, Standard Each
16418483 50 mm 4.6 mm 5 μm Preparative Column, Standard Each
16428483 50 mm 10 mm 5 μm Preparative Column, Standard Each
16438483 50 mm 20 mm 5 μm Preparative Column, Standard Each
16448483 50 mm 25 mm 5 μm Preparative Column, Xtended Life Each
16458483 100 mm 2 mm 5 μm Preparative Column, Standard Each
16468483 100 mm 4.6 mm 5 μm Preparative Column, Standard Each
16478483 100 mm 10 mm 5 μm Preparative Column, Standard Each
16488483 100 mm 20 mm 5 μm Preparative Column, Standard Each
16498483 100 mm 25 mm 5 μm Preparative Column, Xtended Life Each
16408493 150 mm 2 mm 5 μm Preparative Column, Standard Each
16418493 150 mm 4.6 mm 5 μm Preparative Column, Standard Each
16428493 150 mm 10 mm 5 μm Preparative Column, Standard Each
16438493 150 mm 20 mm 5 μm Preparative Column, Standard Each
16448493 150 mm 25 mm 5 μm Preparative Column, Xtended Life Each
16458493 150 mm 30 mm 5 μm Preparative Column, Standard Each
16468493 150 mm 30 mm 5 μm Preparative Column, Xtended Life Each
16478493 150 mm 50 mm 5 μm Preparative Column, Standard Each
16488493 150 mm 50 mm 5 μm Preparative Column, Xtended Life Each
16498493 250 mm 2 mm 5 μm Preparative Column, Standard Each
16408503 250 mm 4.6 mm 5 μm Preparative Column, Standard Each
16418503 250 mm 10 mm 5 μm Preparative Column, Standard Each
16428503 250 mm 20 mm 5 μm Preparative Column, Standard Each
16438503 250 mm 25 mm 5 μm Preparative Column, Xtended Life Each
16448503 250 mm 30 mm 5 μm Preparative Column, Standard Each
16458503 250 mm 30 mm 5 μm Preparative Column, Xtended Life Each
16468503 250 mm 50 mm 5 μm Preparative Column, Standard Each
16478503 250 mm 50 mm 5 μm Preparative Column, Xtended Life Each
16488503 8 mm 10 mm 10 μm Guard Column Each
16498503 20 mm 10 mm 10 μm Guard Column Each
16408513 30 mm 10 mm 10 μm Guard 1/16 in. Each
16418513 30 mm 10 mm 10 μm Guard 1/8 in. Each
16428513 20 mm 20 mm 10 μm Guard Column Each
16438513 30 mm 20 mm 10 μm Guard 1/16 in. Each
16448513 30 mm 20 mm 10 μm Guard 1/8 in. Each
16458513 50 mm 10 mm 10 μm Preparative Column, Standard Each
16478513 50 mm 25 mm 10 μm Preparative Column, Xtended Life Each
16488513 100 mm 10 mm 10 μm Preparative Column, Standard Each
16498513 100 mm 20 mm 10 μm Preparative Column, Standard Each
16408523 100 mm 25 mm 10 μm Preparative Column, Xtended Life Each
16418523 150 mm 10 mm 10 μm Preparative Column, Standard Each
16428523 150 mm 20 mm 10 μm Preparative Column, Standard Each
16438523 150 mm 25 mm 10 μm Preparative Column, Xtended Life Each
16448523 150 mm 30 mm 10 μm Preparative Column, Standard Each
16458523 150 mm 30 mm 10 μm Preparative Column, Xtended Life Each
16468523 150 mm 50 mm 10 μm Preparative Column, Standard Each
16478523 150 mm 50 mm 10 μm Preparative Column, Xtended Life Each
16488523 250 mm 10 mm 10 μm Preparative Column, Standard Each
16498523 250 mm 20 mm 10 μm Preparative Column, Standard Each
16408533 250 mm 25 mm 10 μm Preparative Column, Xtended Life Each
16418533 250 mm 30 mm 10 μm Preparative Column, Standard Each
16428533 250 mm 30 mm 10 μm Preparative Column, Xtended Life Each
16438533 250 mm 50 mm 10 μm Preparative Column, Standard Each
16448533 250 mm 50 mm 10 μm Preparative Column, Xtended Life Each
63 options
This item is not returnable. View return policy

Product Code. 16468513

Brand: Thermo Scientific™ 41110059270A

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Use these preparative columns for scale-up purification with high phase loading. They are suitable for all USP-L7 applications.

Get maximum loading for your scale up from analytical to a prep LC method with Thermo Scientific™ Hypersil™ PREP HS C8 reversed phase preparative HPLC column. With similar selectivity to C18 columns and predictable elution order, C8 columns are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations. By providing high surface area particles with a 100Å pore size, and a variety of dimensions including an option for XtendedLife hardware, which improves column lifetime by maintaining a uniform packed bed.

Similar selectivity, less retention than C18 columns

  • Successful retention and separation of moderately hydrophobic analytes.
  • Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns.
  • C8 (USP L7) selectivity - high surface area particle with 100Å pore size.
  • pH stable from 2 to 8.
  • Maximum temperature of 60°C.

Faster separations

  • Higher analytical throughput compared to C18 alkyl chain chemistry.
  • Quicker compound elution due to reduced hydrophobic interactions.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

  • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
  • Standard threaded hardware for column i.d. < 40mm.
  • Standard flange hardware for column i.d. ≥ 40mm.
  • Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

  • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
  • Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

  • If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
  • Please contact your local sales representative for Customer Specific Orders.
  • Custom built columns are not eligible for returns.
TRUSTED_SUSTAINABILITY

Specifications

Column Format Preparative Column, Standard
Diameter (Metric) 20 mm
Length (Metric) 50 mm
Max. Pressure 4300 psi (295 bar)
Particle Size 10 μm
pH 2 to 8
Pore Size 100 Å
Surface Area 350 m²/g
Temperature 60°C
USP Type L7
Stationary Phase C8
Packing Material Spherical, Fully Porous, Ultrapure Silica
Carbon Load 7%
Column Type Reversed Phase
Endcapped Yes
Phase Reversed Phase
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