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Proteintech HumanKine™ recombinant human IL-34 protein

Product Code. 17610077 Shop All Proteintech Products
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Quantity:
10 μg
100 μg
1000 μg
Unit Size:
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100µg
10µg
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Product Code. 17610077

Brand: Proteintech HZ1316100UG

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This item is not returnable. View return policy

Description

HumanKine™ recombinant protein

IL-34 is a 6-α-helix, proinflammatory cytokine that serves as a ligand for colony-stimulating factor-1 receptor (CSF1R). It is expressed most abundantly by spleen cells. It primarily stimulates human peripheral blood monocyte proliferation and macrophage colony formation. It is also required for Langerhans cell and microglia development. IL-34 has been shown to play a protective role in cancer and Alzheimer’s disease, but it can promote the progression of several autoimmune, inflammatory, and metabolic diseases. As such IL-34 could be used as a biomarker to mark the progression of these diseases (PMID: 22579672, 27577879, 31940023).

Specifications

Accession Number Q6ZMJ4
Formulation 50 mM Acetate pH 4.5 + 75 mM NaCl, See Certificate of Analysis for details
Gene ID (Entrez) 146433
Molecular Weight (g/mol) 68 and 38 kDa
Quantity 100 μg
Source HEK293
Storage Requirements Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.)
Endotoxin Concentration <1 EU/μg
Specific Reactivity Human
Recombinant Recombinant
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Form Lyophilized
Purity or Quality Grade >95%
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