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Description
IL-15 is a 4-α-helix bundle cytokine playing a pivotal role in stimulation of both innate and adaptive immune cells. It is produced primarily by keratinocytes, skeletal muscle cells, monocytes, and CD4+ T cells. It is a member of the common gamma chain family. The members of the common gamma chain family include the IL-2, IL-4, IL-7, IL-9, and IL-21 and require binding to the common chain receptor for activation. It can be used in growth and maintenance of T and NK cells. It is also shown to be used in proliferation and functional effect of T cells for adoptive cell therapy. It is a glycosylated protein and HumanKine IL-15 appear as 12.5-25 kDa bands (PMID: 24587813, 26627006, 27849617, 31250350).
Specifications
Specifications
| Accession Number | P40933 |
| Formulation | 50 mM Acetate pH 4.0 + 150 mM NaCl |
| Gene ID (Entrez) | 3600 |
| Molecular Weight (g/mol) | 11 -23 kDa |
| Quantity | 10 μg |
| Source | HEK293 |
| Storage Requirements | Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.) |
| Endotoxin Concentration | <1 EU/μg |
| Specific Reactivity | Human |
| Recombinant | Recombinant |
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Product Title
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