missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. Proteintech HumanKine™ recombinant human IGF-I protein

Proteintech HumanKine™ recombinant human IGF-I protein

Product Code. 17680087 Shop All Proteintech Products
Click to view available options
Quantity:
10 μg
100 μg
1000 μg
Unit Size:
1000µg
100µg
10µg
This item is not returnable. View return policy

Product Code. 17680087

Brand: Proteintech HZ13221000UG

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

HumanKine™ recombinant protein

The Insulin like growth factor-1, also known as Somatomedin-C is a growth factor which is structurally related to insulin and is an important regulator of growth and differentiation in various tissues and cell systems. Human IGF-1 is synthesized as two precursor isoforms with N- and alternate C-terminal propeptide. The two precursor isoforms are differentially expressed by various tissues. The proteolytic cleavage of the N- and C-terminal regions results in the mature IGF-1 protein which is identical between isoforms. IGF-1 binds to IGF-1 receptor and induces receptor autophosphorylation. This further phosphorylates Insulin receptor substrate -1 (IRS-1) and activates various downstream signaling pathways including the PI3-AKT, MAPK etc. (PMID: 17354613, 17113337, 29535161)

Specifications

Accession Number P05019
Formulation 1 x PBS pH 7.4
Gene ID (Entrez) 3479
Molecular Weight (g/mol) 10 kDa
Quantity 1000 μg
Source HEK293
Storage Requirements Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.)
Endotoxin Concentration <1 EU/μg
Specific Reactivity Human
Recombinant Recombinant
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Activity 2-14 ng/mL EC50
Form Lyophilized
Purity or Quality Grade >95%
Mostrar más Mostrar menos
Corrección del contenido de un producto

Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.

Título del producto

Al hacer clic en Enviar, acepta que Fisher Scientific se ponga en contacto con usted en relación con los comentarios que ha proporcionado en este formulario. No compartiremos su información para ningún otro fin. Toda la información de contacto proporcionada se mantendrá de acuerdo con nuestra Política de Privacidad. Política de privacidad.

Gracias por ayudarnos a mejorar nuestra web. Su comentario ha sido enviado