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Invitrogen™ Human TIMP1 Recombinant Protein

Product Code. 11549051
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Quantity:
1 mg
Unit Size:
1mg
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Product Code. 11549051

Brand: Invitrogen™ RP75735

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This item is not returnable. View return policy

Description

Recombinant Protein

This product contains a purified 184 amino acid fragment (aa24-207) corresponding to the mature TIMP-1 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P01033
Concentration 0.29 mg/mL
For Use With (Application) Control, Western Blot
Formulation 25 mM sodium acetate with 50% glycerol and no preservative; pH 4.8
Gene ID (Entrez) 7076
Molecular Weight (g/mol) 25.21 kDa
Name Human TIMP1
pH Range 4.8
Quantity 1 mg
Source E. coli
Immunogen N/A
Regulatory Status RUO
Gene Alias CLGI; collagenase inhibitor; Collagenase inhibitor 16C8 fibroblast; EG-1; Embryogenin-1; EPA; EPO; erythroid potentiating activity; erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; HCI; Metalloproteinase inhibitor; metalloproteinase inhibitor 1; metalloproteinase tissue inhibitor; metalloproteinase tissue inhibitor 1; MMP inhibitor; RP1-230G1.3; Timp; TIMP 1; TIMP metallopeptidase inhibitor 1; TIMP1; TIMP-1; TIMP-1 protein; tissue inhibitor of matrix metalloproteinase-1; tissue inhibitor of metal proteinases; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); tissue inhibitor of metalloproteinase-1; tissue inhibitor of metalloproteinases; tissue inhibitor of metalloproteinases 1; TPA-induced protein; TPA-S1
Common Name TIMP1
Gene Symbol TIMP1
Conjugate Unconjugated
Species E. coli
Recombinant Recombinant
Protein Tag His-tag
Sequence Amino acids Cys24-Ala207 containing an N-terminal His-tag
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Protein Subtype Recombinant
Purity or Quality Grade >95%, by SDS-PAGE under reducing conditions
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