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ACROBiosystems Human Thrombospondin-2 Protein, His Tag

Brand:  ACROBiosystems TH2-H52H5-1mg

Additional Details : Weight : 0.00010kg

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Product Code. 16448099

  • 32169.11 NOK / 1mg
Estimated Shipment: 20-01-2023
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Description

Description

Thrombospondin-2 is also known as THBS2, TSP2, TSP-2. Thrombospondin-2 (TSP2) is an anti-angiogenic matricellular protein that inhibits tumor growth and angiogenesis. Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. 2 SNPs in the intron region of THBS2 gene (rs6422747 and rs6422748) were associated with susceptibility of IDD. However, they were not related with severity of IDD, including the total number of degenerative disc and level of IDD. Thrombospondin 2, an important regulator of synaptogenesis in central nervous system development, was distributed in retinal macroglia cells, and its receptor α2δ-1 was in retinal neurons. activated macroglia cells may participate in alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure, and macroglia-derived thrombospondin 2 may modulate these changes via binding to its neuronal receptor α2δ-1.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 129.7 kDa. The protein migrates as 160 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_003238.2
129.7 kDa
1 mg
Gly 19 - Ile 1172
Thrombospondin-2,THBS2,TSP2
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human Thrombospondin-2, His Tag (TH2-H52H5) is expressed from human 293 cells (HEK293). It contains AA Gly 19 - Ile 1172 (Accession # P35442-1).
-20°C
Thrombospondin-2
His Tag
Less than 1.0 EU / µg by the LAL method.
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